Topical Exosome Biologics for Licensed Professionals

Wholesale Biologics for Licensed Professionals

Topical Exosome Biologics

3D bioreactor-cultured exosome matrices and secretome systems with NTA-verified particle counts, dual-lab COA testing, and full cGTP compliance. Supplied exclusively to approved wholesale accounts.

AATB Accredited FDA-Registered Facility cGTP-Compliant Dual-Lab COA NTA Particle Verified

Topical Cosmetic Use Only: All exosome and secretome products supplied by Stem Nova Network are intended for topical cosmetic application by licensed professionals. These products are not drugs and are not intended to diagnose, treat, cure, or prevent any disease.

Our Product Line

Flagship Exosome Matrix

3DExo+ 60B Exosome Matrix vial

3DExo+™ 60B Exosome Matrix

Topical Cosmetic Biologic | 1 mL Vial

Our flagship topical cosmetic exosome biologic. 3D bioreactor cultured for consistent particle size and concentration across every lot.

Particle Count 60 Billion NTA-Verified EVs
Culturing 3D Bioreactor Expanded
Verification Dual-Lab COA · NTA Characterized

Secretome Concentrate

Nova Core 66B Secretome Concentrate vial

Nova Core™ Secretome Concentrate — 66B EVs

Topical Cosmetic Secretome | 2 mL Vial

The Step 1 concentrate from the NovaRenew™ system, available standalone. Ideal for practices integrating topical cosmetic secretome into existing post-procedure protocols.

Particle Count 66 Billion NTA-Verified EVs
Volume 2 mL Vial
Verification Dual-Lab COA · NTA Characterized

Premium Dermal Biologic

Dermal Papillary Secretome Matrix+ 150B vial

Dermal Papillary Secretome Matrix+ 150B

Topical Cosmetic Biologic | 1.8 mL Vial

Our highest-concentration topical cosmetic exosome product. Formulated for dermal and hair-follicle cosmetic applications by licensed professionals in aesthetic and hair-restoration settings.

Particle Count 150 Billion NTA-Verified EVs
Volume 1.8 mL Vial
Application Dermal & Hair-Follicle Cosmetic

High-Volume Format

3DExo+ 12B Exosome Matrix 10mL vial

3DExo+™ 12B Exosome Matrix

Topical Cosmetic Biologic | 10 mL Vial

Multi-use format designed for higher-volume topical cosmetic practices. Same 3D bioreactor culturing and NTA verification as the 60B in a larger-volume configuration.

Particle Count 12 Billion NTA-Verified EVs
Volume 10 mL Multi-Use Vial
Verification Dual-Lab COA · NTA Characterized

Complete 2-Step System

NovaRenew 2-Step Secretome System

NovaRenew™ 2-Step Secretome System

Topical Cosmetic Secretome System | 2-Vial Kit

A complete two-step topical cosmetic secretome system designed for post-procedure cosmetic application protocols.

Step 1 Nova Core™ Concentrate (66B EVs)
Step 2 PDRN-Enriched Recovery Serum
Verification Dual-Lab COA · NTA Characterized

Enroll for Wholesale Pricing & Ordering

Approved accounts receive access to wholesale pricing, volume tiers, COA documentation, and direct ordering.

Apply for Wholesale Access

Why Clinics Choose Stem Nova Exosomes

3D Bioreactor Cultured

3D bioreactor expansion produces more consistent particle size, concentration, and composition than flat 2D flask culturing used by most suppliers.

NTA Particle Verification

Nanoparticle Tracking Analysis confirms actual particle count and size distribution — not estimated from protein content. You know exactly what is in each vial.

Dual-Lab COA Testing

Every lot is tested by two independent laboratories for sterility, endotoxin, mycoplasma, and particle characterization. COA documentation included with every order.

No Blood Draw Required

Unlike PRP, topical exosome applications require no blood draw, centrifuge, or patient-side processing. Apply directly after microneedling, RF, or laser procedures.

Common Post-Procedure Applications

Licensed professionals apply topical cosmetic exosomes after these procedures as part of their cosmetic protocols

Microneedling
RF Microneedling
Laser Resurfacing
Hair Restoration Protocols
Chemical Peels
IPL / Photofacial

Topical Exosomes in Your Practice

Many practices use topical cosmetic exosomes alongside PRP and other protocols. Here is how they compare operationally:

Consideration Topical Exosomes PRP
Blood draw required No Yes
Centrifuge / processing None 15–20 min
Batch consistency Standardized (COA verified) Patient-dependent
Shelf life Months (refrigerated) Use immediately
Staff time per treatment Minimal (apply topically) 30+ min total
Can be combined? Yes — many practices use both in tandem as part of their protocols

Comparison reflects operational and logistical differences only. SNN makes no claims regarding clinical superiority of any product over another.

What’s Included with Every Order

Dual-lab Certificate of Analysis (COA)
NTA particle characterization report
Lot-specific sterility and endotoxin data
Refrigerated shipping with temperature monitoring
Handling and storage documentation
Dedicated wholesale account manager

Frequently Asked Questions

What does NTA-verified mean?

Nanoparticle Tracking Analysis (NTA) uses laser light scattering to measure the actual number and size distribution of extracellular vesicles in each lot. Unlike protein-based estimates, NTA provides a direct particle count — so the 60 billion on the label reflects 60 billion verified particles.

What is the difference between 3D and 2D culturing?

Most suppliers expand cells in flat 2D flasks. Stem Nova’s lab partner uses 3D bioreactor systems that more closely replicate physiological conditions, producing more consistent particle size and concentration across batches compared to 2D methods.

Can I use exosomes alongside PRP?

Yes. Many practices apply topical cosmetic exosomes as a complement to PRP protocols. The two can be used in tandem within cosmetic procedure workflows at the clinician’s discretion.

How should I store the products?

Exosome products are shipped refrigerated and should be stored at 2–8°C upon arrival. Do not freeze. Refer to the product-specific handling guide included with each shipment for detailed storage and expiration information.

Who can order exosome products?

Only licensed medical professionals (MD, DO, NP, PA) with an approved Stem Nova Network wholesale account. Apply through our enrollment portal — approval typically takes 1–2 business days.

Which product is right for my practice?

It depends on your procedure mix and volume. Nova Core™ 66B and 3DExo+™ 12B offer larger-volume formats for high-throughput practices. 3DExo+™ 60B and Dermal Papillary 150B are our premium single-vial options. NovaRenew™ provides a complete two-step system. Our team can help you choose — contact us for a product consultation.

Is there a minimum order quantity?

No minimum order is required. Approved accounts may order as few as one vial or kit. Volume pricing is available for practices with recurring needs.

Also Available: UCT-MSC Stem Cells

Licensed professionals also ordering research-grade 25M hUCT-MSC vials through Stem Nova Network.

25M hUCT-MSC Stem Cell Vial

25M hUCT-MSC Vial

Wharton’s Jelly · Dual-Lab COA · Cryopreserved

Ready to Open a Wholesale Account?

Apply in under 5 minutes. Approved clinics receive access to wholesale pricing, COA documentation, and dedicated support.

Regulatory Notice: Exosome and secretome products supplied by Stem Nova Network are topical cosmetic biologics intended for external cosmetic application by licensed medical professionals. These products are not drugs and are not FDA-approved for the diagnosis, treatment, cure, or prevention of any disease. Products are manufactured at an AATB-accredited, FDA-registered tissue establishment under cGTP regulations (21 CFR Part 1271). Product availability is limited to licensed medical professionals with an approved wholesale account. Clinical decisions remain the sole responsibility of the treating physician.