What Is a Certificate of Analysis?

A Certificate of Analysis (COA) is a lot-specific document issued by an independent testing laboratory that reports the results of quality-control testing performed on that batch of product. It provides objective, third-party verification that the product meets defined specifications for identity, purity, sterility, and composition.

For biologic products, a COA is one of the most important documents a practitioner can request from a supplier. It is how you verify that what is on the label matches what is in the vial.

SNN's Dual-Lab Testing Standard

Most suppliers provide a single-lab COA. Stem Nova Network requires every lot to be tested by two independent laboratories. This dual-lab approach reduces the risk of false results and provides an additional layer of verification for your practice.

NTA Particle Verification

Nanoparticle Tracking Analysis (NTA) uses laser light scattering to directly measure the number and size distribution of extracellular vesicles in each lot. Unlike protein-based estimates (such as BCA assays), NTA provides a direct particle count.

This distinction matters: when a label states "60 billion exosomes," NTA verification means the count was measured — not estimated from total protein content, which can include non-vesicle proteins and overstate the actual particle number.

Every SNN exosome product includes an NTA characterization report in addition to the dual-lab COA.

Requesting Documentation

All documentation is included automatically with every order. Approved wholesale accounts can also request documentation in advance of placing an order for review purposes.

If you are evaluating Stem Nova Network as a potential supplier and would like to review sample documentation before applying for a wholesale account, contact our team to request sample COA and NTA reports.