Frequently Asked Questions

Wholesale Biologics for Licensed Professionals

Frequently Asked Questions

Answers to common questions from licensed professionals about our products, ordering process, documentation, and compliance.

About Stem Nova Network

What is Stem Nova Network?

Stem Nova Network is a Texas-based B2B wholesale supplier of biologic products — including topical cosmetic exosome biologics, UCT-MSC stem cells, and wholesale peptides — for licensed medical professionals. We supply exclusively to approved wholesale accounts held by practitioners with valid medical licensure.

Who can purchase from Stem Nova Network?

Only licensed medical professionals — physicians (MD, DO), nurse practitioners (NP), physician assistants (PA), and their authorized practice entities. All applicants are verified for valid licensure before account approval. We do not sell to consumers, unlicensed individuals, or non-medical entities.

Where are your products sourced?

Our biologic products are sourced from an AATB-accredited, FDA-registered tissue establishment operating under cGTP regulations (21 CFR Part 1271). Exosome products are manufactured using 3D bioreactor culturing technology, and stem cell products are derived from Wharton's jelly tissue from an AATB-accredited establishment with this tissue category within scope of accreditation.

Products

What exosome products do you offer?

We supply several topical cosmetic exosome and secretome products: 3DExo+™ 60B (1 mL, 60 billion NTA-verified EVs), Nova Core™ 66B (2 mL secretome concentrate), Dermal Papillary Secretome Matrix+ 150B (1.8 mL), 3DExo+™ 12B (10 mL multi-use format), and the NovaRenew™ 2-Step Secretome System. Visit our Exosome Biologics page for full product details.

What is the difference between 3D and 2D culturing?

Most exosome suppliers expand cells in flat 2D flasks. Stem Nova's lab partner uses 3D bioreactor systems that more closely replicate physiological conditions, producing more consistent particle size and concentration across batches compared to 2D methods.

What does NTA-verified mean?

Nanoparticle Tracking Analysis (NTA) uses laser light scattering to measure the actual number and size distribution of extracellular vesicles in each lot. Unlike protein-based estimates, NTA provides a direct particle count — so the 60 billion on the label reflects 60 billion verified particles.

How should I store the products?

Exosome products should be stored at −80°C upon arrival. Stem cell vials are shipped cryopreserved and stored according to the lot-specific handling guide included with each shipment. Refer to product-specific documentation for detailed storage and expiration information.

Which product is right for my practice?

It depends on your procedure mix and volume. Our team can help you evaluate options based on your practice's needs — contact us for a product consultation.

Ordering & Accounts

How do I apply for a wholesale account?

Submit your application through our enrollment portal. You will provide your medical license information, practice details, and shipping information. The application takes under 5 minutes. Visit How Wholesale Works for the full enrollment process.

How long does approval take?

Most applications are reviewed within 1–2 business days. You will receive an email confirmation once your account is active and ready to place orders.

Is there a minimum order?

No. Approved accounts may order as few as one vial or kit. Volume pricing is available for practices with recurring ordering needs.

What payment methods do you accept?

We accept all major credit cards and ACH bank transfer through our secure online portal. Invoicing options are available for qualifying accounts — contact your account manager for details.

Can my office staff place orders on behalf of our practice?

Yes. The wholesale account is tied to the licensed practitioner, but authorized staff members can access the order portal to place and manage orders on the practice's behalf.

Shipping & Handling

How are products shipped?

All biologic products ship via cold-chain with temperature monitoring. Exosome products ship frozen on dry ice; stem cell products ship cryopreserved. Packaging protocols are designed to maintain product integrity from our warehouse to your practice.

What documentation comes with each order?

Every order includes lot-specific dual-lab Certificate of Analysis (COA), NTA particle characterization report, sterility and endotoxin testing data, and handling and storage documentation. Visit Documentation & COAs for details about our testing standards.

What if a product arrives damaged or compromised?

Contact your dedicated account manager immediately if a shipment arrives damaged, with a broken cold-chain seal, or if temperature monitoring indicates a deviation. Do not use any product that may have been compromised during transit.

Compliance & Regulatory

Are your products FDA-approved?

No. Exosome and secretome products are topical cosmetic biologics — they are not drugs and are not FDA-approved for the diagnosis, treatment, cure, or prevention of any disease. Stem cell products are research-grade biologics that are not FDA-approved. Our sourcing facility is FDA-registered as a tissue establishment, which means it has registered with the FDA under 21 CFR Part 1271 — this is not the same as FDA approval.

What does "cGTP-compliant" mean?

Current Good Tissue Practice (cGTP) regulations, defined in 21 CFR Part 1271, are FDA requirements governing the methods used in the manufacture of human cells, tissues, and cellular and tissue-based products (HCT/Ps). cGTP compliance means the facility follows these regulations for donor screening, processing, storage, labeling, and distribution.

What does AATB accreditation mean?

The American Association of Tissue Banks (AATB) is the standard-setting body for tissue banking in the United States. AATB accreditation is a voluntary certification indicating that the tissue establishment meets the AATB's standards for tissue procurement, processing, storage, and distribution. It is an additional quality benchmark beyond the FDA's regulatory requirements.

What is the intended use of exosome products?

All exosome and secretome products from Stem Nova Network are intended for topical cosmetic application by licensed professionals. Common applications include post-procedure use after microneedling, RF microneedling, laser resurfacing, and similar cosmetic procedures. These products are not intended for injection or for any therapeutic or diagnostic purpose.

Have Another Question?

Our team is available to answer questions about products, documentation, ordering, or compliance.

Regulatory Notice: Products supplied by Stem Nova Network are intended for use by licensed medical professionals only. Exosome and secretome products are topical cosmetic biologics not intended to diagnose, treat, cure, or prevent any disease. Stem cell products are research-grade biologics that are not FDA-approved. Products are sourced from an AATB-accredited, FDA-registered tissue establishment under cGTP regulations (21 CFR Part 1271). Clinical decisions remain the sole responsibility of the treating physician. For complete terms, see our Medical & Legal Disclaimer.