{"product_id":"3dexo-12b-exosome-matrix-topical-cosmetic","title":"3DExo+™ 12B Exosome Matrix — Topical Cosmetic Biologic for Licensed Professionals","description":"\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eAbout This Product\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e3DExo+™ Matrix with Growth Factor is a topical cosmetic exosome serum supplied exclusively to licensed medical professionals. Each 10 mL vial contains 12 billion NTA-verified extracellular vesicles derived from 3D bioreactor-cultured Wharton's Jelly UCT-MSCs, sourced from an AATB-accredited, FDA-registered tissue establishment operating under cGTP standards (21 CFR Part 1271).\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eFor topical cosmetic use only. Not for injection or therapeutic use. Not FDA-approved.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhy 3D Bioreactor Culture\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eMost exosome products are produced using standard 2D flat-surface cell culture. Stem Nova Network uses 3D hollow-fiber bioreactor systems that allow cells to grow in three dimensions. Published research has documented up to 19.4x higher extracellular vesicle yield per cell from 3D bioreactor systems compared to conventional 2D flat culture. This is a manufacturing process distinction, not a clinical outcomes claim.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eProduct Specifications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003e12 Billion EVs per vial — NTA-verified particle count, lot-documented\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eVolume: 10 mL per vial\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003e3D bioreactor-cultured source cells — Wharton's Jelly UCT-MSC origin\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eFirst-pregnancy donors — full donor screening on record\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eClassification: Cosmetic-grade topical serum · Non-injectable · Non-biologic\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eLightweight, fast-absorbing formulation — no residue\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eXeno-Free · Serum-Free · Endotoxin-tested\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eCell-free matrix — no live or viable cells\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSourced from an AATB-accredited, FDA-registered tissue establishment operating under cGTP standards (21 CFR Part 1271)\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eLot-specific Certificate of Analysis with every order\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eSterility tested per 21 CFR 610.12 · Mycoplasma tested prior to release\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRecommended Professional Applications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePost-microneedling topical application\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eProfessional facial and skin rejuvenation treatments\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003ePost-laser and fractional resurfacing recovery\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eLED light therapy recovery protocols\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eAesthetic post-procedure topical support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eQuality \u0026amp; Testing\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eEvery lot is independently tested and released with a Certificate of Analysis covering particle count via NTA, sterility, mycoplasma, endotoxin, and size distribution. Documentation is available upon request before purchase.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eSourcing from an AATB-accredited, FDA-registered tissue establishment operating under cGTP standards (21 CFR Part 1271) are manufacturing and facility credentials. They do not constitute FDA approval of this product for any therapeutic indication.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eHow to Order\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e3DExo+™ 12B is available to licensed medical professionals only. Credential verification is required prior to purchase.\u003c\/p\u003e\n\u003cul class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eApply for wholesale access at stemnovanetwork.com\/apps\/wpdapp\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eCredential verification completed within 24 hours in most cases\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eOnce approved, wholesale pricing and volume tiers are unlocked immediately\u003c\/li\u003e\n\u003cli class=\"whitespace-normal break-words pl-2\"\u003eLot-specific CoA provided with every order\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eContact \u003ca class=\"underline underline underline-offset-2 decoration-1 decoration-current\/40 hover:decoration-current focus:decoration-current\" href=\"mailto:partners@stemnovanetwork.com\"\u003einfo@stemnovanetwork.com\u003c\/a\u003e or call 281-541-0047 with any questions.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat is the shelf life and storage requirement?\u003c\/strong\u003e 3DExo+™ 12B ships liquid cryopreserved on dry ice. Store at -80°C or below upon receipt. Thaw at room temperature or in a 37°C water bath immediately before use. Use within 1 hour of thawing. Do not refreeze after thawing.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eIs a Certificate of Analysis included with every order?\u003c\/strong\u003e Yes. Every wholesale order includes a lot-specific CoA covering NTA particle count, sterility, mycoplasma, endotoxin, and size distribution. Documentation is also available on request before purchase.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat is NTA verification and why does it matter?\u003c\/strong\u003e Nanoparticle Tracking Analysis is the gold standard method for confirming actual particle count and size distribution in an exosome preparation. NTA-verified counts reflect what is in the vial as shipped — not estimated or derived figures.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eWhat is the difference between the 12B and 60B vials?\u003c\/strong\u003e The 12B is formulated as a 10 mL cosmetic-grade topical serum designed specifically for facial, post-procedure, and medspa protocols requiring a larger application volume. The 60B delivers a higher concentration in a 1 mL vial, suited for targeted topical applications. Both are derived from the same 3D bioreactor-cultured Wharton's Jelly UCT-MSC source and are for topical cosmetic use only.\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eIs this product FDA-approved?\u003c\/strong\u003e No. 3DExo+™ 12B is not an FDA-approved drug or therapeutic agent. There are currently no FDA-approved exosome products. This product is supplied as a cosmetic-grade topical serum for licensed professional use only.\u003c\/p\u003e\n\u003chr class=\"border-border-200 border-t-0.5 my-3 mx-1.5\"\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003e\u003cstrong\u003eRegulatory Notice\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal leading-[1.7]\"\u003eThis product is supplied as a cosmetic-grade topical serum for licensed professional use only. It is not an FDA-approved drug or therapeutic agent and is not intended to diagnose, treat, cure, or prevent any disease or condition. For topical cosmetic use only. Not for injection or therapeutic use. All professional application decisions are at the sole discretion of the licensed practitioner in accordance with applicable federal and state regulations.\u003c\/p\u003e","brand":"Stem Nova","offers":[{"title":"Default Title","offer_id":55604470219135,"sku":"SNN-EXO-12B-10ML","price":225.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0913\/8903\/4879\/files\/12bn_exosomes_10mL.jpg?v=1775140574","url":"https:\/\/www.stemnovanetwork.com\/products\/3dexo-12b-exosome-matrix-topical-cosmetic","provider":"Stem Nova","version":"1.0","type":"link"}